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Vinoth, N.
- Modelling of Four Compartment Model of Cardiovascular System using Simulation
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1 Department of Electronics and Instrumentation Engineering, Annamalai University, Annamalai Nagar, Tamilnadu, IN
2 Department of Electronics and Instrumentation Engineering, Annamalai University, Annamalai Nagar, Tamilnadu, IN
1 Department of Electronics and Instrumentation Engineering, Annamalai University, Annamalai Nagar, Tamilnadu, IN
2 Department of Electronics and Instrumentation Engineering, Annamalai University, Annamalai Nagar, Tamilnadu, IN
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Biometrics and Bioinformatics, Vol 5, No 1 (2013), Pagination: 1-6Abstract
Cardiovascular system is one of the main systems of our human body. There are several cardiovascular problems that have a significant effect on health expenditures in industrialized countries; moreover it reduces patient’s quality of life. In this point of view, current research focuses on detailed modeling of the cardiovascular system. Thus, this paper aims to present a model of the heart enhanced with a widespread model of the cardiovascular system. A mathematical description of this system can provide more insight. So computer-based simulation of the cardiovascular system is analyzed and simulation is done using matlab/simulink software. Instead of a hydraulic model, an inexpensive, compact and simple electrical circuit consisting of resistances, capacitances, inductances and diodes has been constructed, using parametric values that are transformed from hydraulic models. In order to obtain the more accurate model than those used in prior investigations in the literature, a baroreceptor model has been introduced. The model outputs are flow/pressure waveforms, which exhibit a similarity with physiological curves. The elastance was modeled in the form of sine wave which has a parameter H. The parameter H present in the sine wave was altered, corresponding arterial pressure is obtained. Optimal parameter H input to sin wave is found.Keywords
Cardiovascular System, Heart, Modelling, Pressure.
- Recent Studies on the Drug Delivery of Nebulizers - A Review
Abstract Views :143 |
PDF Views:1
Authors
Affiliations
1 School of Mechanical Engineering, Vellore Institute of Technology, Chennai Campus, Vandalur-Kelambakkam Road, Chennai – 600127, Tamil Nadu, IN
1 School of Mechanical Engineering, Vellore Institute of Technology, Chennai Campus, Vandalur-Kelambakkam Road, Chennai – 600127, Tamil Nadu, IN
Source
Journal of Surface Science and Technology, Vol 37, No 3-4 (2021), Pagination: 131-140Abstract
This article provides a summary of some of the most current research on the delivery of drugs to the lungs, as well as a discussion of some of the limitations of these studies. Nebulizers have been in use for more than a century to deliver aerosolized drugs to patients suffering from respiratory disorders. Aerosol devices such as these are the best option for people who have trouble managing their inhalation. Because of the actuation required, pressurised Metered-Dose Inhalers (pMDI) and Dry Powder Inhalers (DPI) are unable to generate the necessary inspiratory flow required for successful aerosol drug delivery. Currently, we are looking into how the working mechanism of different nebulizers interacts with the physicochemical features of the formulations. We are looking into a wide range of devices, such as jet, ultrasonic, and vibrating-mesh nebulizers. In this study, the researchers hope to describe the many different types of nebulizers that are currently available on the market, evaluate their performance in aerosol drug delivery, and recommend treatment approaches for patients with chronic obstructive pulmonary disease.Keywords
Aerosol, Atomizer, Computational Fluid Dynamics (CFD), Dew Size, Drug Delivery, Nebulization, Nebulizer.References
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